Contact: Leigh MacMillan
leigh.macmillan@vanderbilt.edu
615-322-4747
Vanderbilt University Medical Center

Fluorescent Immunostaining of Dorsal Root Ganglion Cells

Caption: Neurons (green) and glial cells from isolated dorsal root ganglia express COX-2 (red) after exposure to an inflammatory stimulus (cell nuclei are blue). Lawrence Marnett and colleagues have demonstrated that certain drugs selectively block COX-2 metabolism of endocannabinoids -- naturally occurring analgesic molecules -- in stimulated dorsal root ganglia.

Credit: Lawrence Marnett and colleagues and Nature Chemical Biology

Usage Restrictions: Please credit Lawrence Marnett and colleagues and Nature Chemical Biology

Related news release: Study puts a new spin on ibuprofen's actions