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Contact: Hema Bashyam
Cold Spring Harbor Laboratory

Mice with 16p11.2 Deletion Exhibit Non-progressive Behavior

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Caption: Climbing episodes of wild type mice (right) and mice with 16p11.2 deletion (left) during the first 10 hours of the experiment. At the beginning of the trial, both mice climb to the lower part of the cage ceiling, returning to the floor with their hindlimbs leading. Later on in the trial, wild type mice progress until they reach the highest point of the ceiling of the cage, returning to the floor from different ceiling areas with their forelimbs leading. In contrast, 16p11.2 deletion mice lack this progressive behavior, exhibiting the same behavior as earlier in the trial.

Credit: Image courtesy of Horev@CSHL

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