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Rockefeller University Press

Liver Cells Lacking GAPDH

Caption: A new study in the Journal of Cell Biology suggests that differential expression of GAPDH and NDPK, two key metabolic enzymes, may explain why some people are more susceptible to liver damage.Compared to control cells (left), liver cells lacking GAPDH (right) show increased levels of reactive oxygen species (green) after treatment with the liver-damaging drug DDC.

Credit: Image courtesy of Snider, N.T., et al. 2011. J. Cell Biol. doi:10.1083/jcb.201102142

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