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Contact: Bonnie Ward
La Jolla Institute for Allergy and Immunology

T Cells Attack Pancreatic Islets

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Caption: This video shows the T cells (purple dots) attacking the pancreatic islets (green images in center), which contain the insulin‑producing beta cells. (Beta cell destruction leads to type 1 diabetes). The squiggly "tail" on the T cells, which switches from blue to red to yellow, is a tracking mechanism inserted by the researchers to record the T cell's velocity and attack time. The attack continues over several hours before a number of beta cells are destroyed.

Credit: Video by La Jolla Institute for Allergy & Immunology.

Usage Restrictions: Media may post or broadcast the video, provided they include a reference to JCI (such as "video published by the Journal of Clinical Investigation") and also a link to the full article as follows: http://www.jci.org/articles/view/59285. (movie links at end of paper).

Related news release: La Jolla Institute researchers provide world's first view of Type 1 diabetes as it unfolds

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