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Contact: David Cameron
david_cameron@hms.harvard.edu
617-432-0441
Harvard Medical School

Predictive Power

Caption: Studying related proteins, researchers identified pairs of amino acid residues (left) that seemed to change in lockstep in the evolutionary record. These co-varying pairs indicated points on protein (middle) likely to be in contact after folding, giving researchers enough clues to create a computational model of the protein's three-dimensional structure (right).

Credit: Terry Helms/Memorial Sloan-Kettering Cancer Center

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Related news release: Evolution reveals missing link between DNA and protein shape


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