Helical vs. Random Coil Polymers as Gene Delivery Agents (image) University of Illinois at Urbana-Champaign Share Print E-Mail Caption Polymers as gene delivery agents. Helical charged polypeptides, left, deliver DNA to the cell by rupturing the endosomal membrane. Random-coil polymers, right, do not rupture the membrane, so the DNA is not released inside the cell. Credit Nathan Gabrielson Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.