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Contact: Liz Ahlberg
University of Illinois at Urbana-Champaign

Helical vs. Random Coil Polymers as Gene Delivery Agents

Caption: Polymers as gene delivery agents. Helical charged polypeptides, left, deliver DNA to the cell by rupturing the endosomal membrane. Random-coil polymers, right, do not rupture the membrane, so the DNA is not released inside the cell.

Credit: Nathan Gabrielson

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