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Contact: Diana Lutz
dlutz@wustl.edu
314-935-5272
Washington University in St. Louis

Plasmodium Enzyme Phosphoethanolamine Methyltransferase

Caption: A cartoon based on the electron density map makes it easier to see the protein's structure and figure out how it works. The enzyme's job is to add a methyl group -- three times -- to a starting molecule as part of a process for making cell membranes. In this cartoon, the phosphate is a stand-in for the starting molecule and the green molecule is the one that donates a methyl group. Both are positioned in the active site of the enzyme, the pocket where the chemistry takes place.

Credit: Joseph Jez

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