Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

Lifespan Methylation Trajectories

Caption: Two representative genes show strikingly opposite trajectories of PFC methylation across the lifespan. Each dot represents a different brain. Usually, the more methylation, the less gene expression.

Credit: Barbara Lipska, Ph.D., NIMH Clinical Brain Disorders Branch

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