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Contact: Jim Dryden
Washington University School of Medicine

FAS-Deficient Mice

Caption: In mice without the key enzyme, fatty acid synthase, bad bacteria invade the colon and the small intestine, which creates the inflammation underlying insulin resistance and diabetes. In the mouse colon above, a protein (shown in red) that makes up the protective membrane in the gut is not functioning properly.

Credit: Washington University School of Medicine

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