MLN4924 (image) Sanford-Burnham Medical Research Institute Caption Cancer cells with a simple mutation in the NEDD8-activating enzyme become resistant to experimental cancer drug MLN4924. Credit Sanford-Burnham Medical Research Institute Usage Restrictions Free to use in conjunction with this story, using provided caption and credit. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.