Contact: Anne DeLotto Baier
University of South Florida (USF Health)
Caption: This is a microscopic image showing co-localization of a fragment of the amyloid precursor protein, known as sAPP-α, with BACE1, an enzyme involved in the development of characteristic Alzheimer's amyloid deposits. This merging suggests sAPP-α may serve as a mechanism to inhibit BACE1 activity and thus lower production of toxic amyloid beta associated with Alzheimer's disease.
Credit: © University of South Florida
Usage Restrictions: Please use appropriate caption.
Related news release: Alzheimer's precursor protein controls its own fate, study finds