Contact: Anne DeLotto Baier
abaier@health.usf.edu
813-974-3303
University of South Florida (USF Health)

Co-Localization of sAPP-α and BACE1 in Neuronal Cells

Caption: This is a microscopic image showing co-localization of a fragment of the amyloid precursor protein, known as sAPP-α, with BACE1, an enzyme involved in the development of characteristic Alzheimer's amyloid deposits. This merging suggests sAPP-α may serve as a mechanism to inhibit BACE1 activity and thus lower production of toxic amyloid beta associated with Alzheimer's disease.

Credit: © University of South Florida

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