Secondary Speckle Sensing Microscopy (image) The Optical Society Caption The difference between an infected red blood cell (top) and a healthy cell (bottom) is revealed by S3M, in part, by considering the dynamics of the correlation value (CV). CV indicates the similarity between two patterns. 1,000 CVs are calculated from pairs of consecutive speckles acquired in 1 second. As shown in the chart at right, the CV oscillation range for the infected cell (top, 0.36) is almost three times larger than that of the healthy red blood cell (bottom, 0.13). In the top left image of the infected cell a parasitic life-cycle stage of malaria, called "trophozoite," can be seen (arrow). Credit Dan Cojoc, Materials Technology Institute, National Research Council, Italy. Usage Restrictions None Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.