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Contact: Gina Kirchweger
gxk@stowers.org
816-806-1036
Stowers Institute for Medical Research
Caption: Mutants lacking Chd1 have difficulty recreating the proper nucleosome array after gene expression. Each row represents a genic nucleosomal array; arrays are sorted by array length and aligned by array midpoint (illustrated above the plot). Blue areas are the nucleosome free regions found at the beginning and end of genes. Color bar represents the nucleosomal occupancy from dark blue (zero) to green (genomic average) to dark red (twice the genomic average). Top: wild type yeast. Bottom: Chd1 mutant yeast.
Credit: Image courtesy of the Shilatifard Lab
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Related news release: Control of gene expression: Histone occupancy in your genome
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