Contact: Steve Chaplin
Caption: The black region shows normal adhesion, with each black axis an independent type of adhesion failure. The red region shows adhesion defects making invasion most likely, as the yellow arrow denotes increasing risk of blood vessel invasion in the retinal pigment epithelium (RPE) lining. The blue arrow follows reduced adhesion but with no increased risk of sub-RPE invasion; green arrow shows reduced adhesion between RPE and photoreceptors (POS) from impaired retina, reducing risk of sub-RPE invasion but increasing risk of other types of invasion.
Credit: Indiana University Biocomplexity Institute
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