Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Liver Fat Gets a Wake-Up Call

Caption: This image shows a high-fat-diet (HFD)-induced fatty liver in wild-type mice, characterized by big lipid droplets in liver cells (top). Liver-specific HDAC3 knockout mice on HFD, note that the lipid droplets become smaller even though the total lipid content is increased (bottom).

Credit: Mitchell Lazar, M.D., Ph.D.; Zheng Sun, Ph.D., Perelman School of Medicine, University of Pennsylvania; Nature Medicine

Usage Restrictions: None

Related news release: Liver fat gets a wake-up call that maintains blood sugar levels