PEDEA4 Hypoxia (image) Max-Planck-Gesellschaft Caption This image shows the formation of PDE4 in oxygen-deficient lung tumor cells. Lung cells produce PDE4 (stained green: left) even if their oxygen content is normal. More PDE4 is produced (right) if they are oxygen-deficient (hypoxia). The cell nuclei are stained blue. Credit MPI for Heart and Lung Research Usage Restrictions None Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.