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Contact: Kris Rebillot
Buck Institute for Age Research

Striatal Neurons Generated from Corrected iPSCs

Caption: Huntington's disease results in massive loss of cells in the brain, particularly in regions called the cortex and striatum. The cells depicted are from a patient with HD - they have been genetically corrected. These are striatal neurons which are expressing DARPP-32 and beta-III-tubulin, markers of neurons lost in HD.

Credit: Ellerby lab, Buck Institute

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Related news release: Buck scientists correct Huntington's disease mutation in induced pluripotent stem cells

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