Contact: Heather Buschman, Ph.D.
Sanford-Burnham Medical Research Institute
Caption: APJ's yin-yang role in cardiac function: the receptor APJ serves a dual function in heart health, depending on how itís activated. While APJ enhances heart health upon binding the hormone apelin (green), APJ can also trigger heart enlargement and failure when it senses certain mechanical changes (red).
Credit: Sanford-Burnham Medical Research Institute
Usage Restrictions: Free to use in conjunction with stories about this study only, using provided caption and credit.
Related news release: Discovery of new heart failure trigger could change the way cardiovascular drugs are made