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Contact: Heather Buschman, Ph.D.
Sanford-Burnham Medical Research Institute

APJ's Yin-Yang Role in Cardiac Function

Caption: APJ's yin-yang role in cardiac function: the receptor APJ serves a dual function in heart health, depending on how itís activated. While APJ enhances heart health upon binding the hormone apelin (green), APJ can also trigger heart enlargement and failure when it senses certain mechanical changes (red).

Credit: Sanford-Burnham Medical Research Institute

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