Contact: Susan Craig
sc2756@columbia.edu
212-305-9746
Columbia University Medical Center

Does Bone Help Control Metabolism and Weight?

Caption: A skeleton hand controlling the fate of a series of sugar cubes through a domino effect. In the Aug. 10 issue of Cell, CUMC researchers present genetic evidence indicating that the skeleton is an endocrine organ regulating energy metabolism via 3 synergistic actions: regulation of pancreatic B-cell proliferation, insulin secretion and insulin sensitivity.

Credit: Karsenty Lab, Columbia University Medical Center, August 2007.

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Related news release: Research shows skeleton to be endocrine organ