Contact: Bill Schaller
Dana-Farber Cancer Institute
Caption: Bruce Spiegelman, PhD, and his colleagues have identified the first known molecular link between thermogenesis (burning calories to produce heat) and the development of inflammation in fat cells. Flipping the newly discovered molecular switch in white fat cells enabled mice to eat a high-calorie diet without becoming obese or developing the inflammation that causes insulin resistance.
Credit: Sam Ogden
Usage Restrictions: None
Related news release: Scientists find molecular link to obesity and insulin resistance in mice