CFTR Functionality (image) Rockefeller University Press Share Print E-Mail Caption A new JGP study provided evidence about the functionality of CFTR, a protein that plays a critical role in cystic fibrosis. Here, an updated model illustrates the relationship between an opening/closing cycle of the gate and ATP consumption in CFTR's nucleotide-binding domains. Credit Jih, K.-Y., et al. 2012. J. Gen. Physiol. 140:347-359. Usage Restrictions Reporters may freely use these materials in news coverage, with the appropriate credit information. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.