Contact: Karen Kreeger
karen.kreeger@uphs.upenn.edu
215-349-5658
University of Pennsylvania School of Medicine

Parkinson's Disease Protein Causes Disease Spread and Neuron Death

Caption: The image shows the substantia nigra of a wildtype mouse 3 months following the injection of a-syn fibrils. The red represents the misfolded form of a-syn and reveals its accumulation as inclusions in dopamine neurons that are labeled green. This pathology is accompanied by a progressive loss of motor function in these fibril-inoculated animals.

Credit: Kelvin C. Luk, PhD, Perelman School of Medicine, University of Pennsylvania

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