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Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Parkinson's Disease Protein Causes Disease Spread and Neuron Death

Caption: The image shows the substantia nigra of a wildtype mouse 3 months following the injection of a-syn fibrils. The red represents the misfolded form of a-syn and reveals its accumulation as inclusions in dopamine neurons that are labeled green. This pathology is accompanied by a progressive loss of motor function in these fibril-inoculated animals.

Credit: Kelvin C. Luk, PhD, Perelman School of Medicine, University of Pennsylvania

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Related news release: Parkinson's disease protein causes disease spread and neuron death in healthy animals

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