Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Rhomboid Protease Cuts Unstable Target Protein

Caption: The membrane encourages a coil to form in a target protein (left, pink and yellow) and helps keep the gate (pale blue) of the rhomboid protease (deep blue) from swinging open too far (center). When the target protein enters the watery interior of the rhomboid protease, the upper section of its coil (yellow) falls apart and gets cut (right).

Credit: eLife Journal, Creative Commons License, courtesy of Sin Urban

Usage Restrictions: Creative Commons License, credit eLife journal

Related news release: Location, location, location: Membrane 'residence' gives proteases novel abilities