X-Ray Laser Pulses Reveal Key Parasite Enzyme (2 of 15) (image) American Association for the Advancement of Science Share Print E-Mail Caption Scanning electron micrograph of an in vivo grown Trypanosoma brucei cathepsin B microcrystal that grew in an Sf9 insect cell and was extracted. Cathepsin B is an enzyme that is essential to the T. brucei parasite and so is a potential target to develop a cure for African sleeping sickness. The molecular structure of the enzyme was solved from almost 200,000 individual microcrystals. This image relates to a paper that appeared in the Nov. 29, 2012, issue of Science Express, published by AAAS. The paper, by Lars Redecke at the University of Hamburg in Hamburg, Germany, and colleagues was titled, "Natively Inhibited Trypanosoma brucei Cathepsin B Structure Determined Using an X-ray Laser." Credit Image courtesy of Karol Nass, CFEL Usage Restrictions Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.