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Contact: Mary Beth OLeary
Cell Press

Revolutionary Techniques Could Help Harness Patients' Own Immune Cells to Fight Disease

Caption: The human body contains immune cells programmed to fight cancer and viral infections, but they often have short lifespans and are not numerous enough to overcome attacks by particularly aggressive malignancies or invasions. Now researchers reporting in two separate papers in the Jan. 4 issue of the Cell Press journal Cell Stem Cell used stem cell technology to successfully regenerate patients' immune cells, creating large numbers that were long-lived and could recognize their specified targets: HIV-infected cells in one case and cancer cells in the other. The findings could help in the development of strategies to rejuvenate patients' exhausted immune responses.

Credit: Vizcardo et al., Cell Stem Cell

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