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Caption: Morphology of DCs changes from the immadurate stage (A) to madurate stage (C). Immadurate cells (A) are those that contact with the microorganism and, thereafter madurate to migrate to lymph node and present the antigen to CD4 T lymphocytes (C). This image relates to a paper that appeared in the Jan. 2, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by F. García at University of Barcelona in Barcelona, Spain, and colleagues was titled, "A Dendritic Cell-Based Vaccine Elicits T Cell Responses Associated with Control of HIV-1 Replication."
Credit: Image courtesy of Dr. Felipe García, IDIBAPS - Hospital Clínic de Barcelona
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