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Hypoxic Vessels in a Breast Tumor

Caption: This shows severely hypoxic areas of a breast tumor (Black and dark blue on right), where sickle cells clump and bind.

Credit: Terman DS, Viglianti BL, Zennadi R, Fels D, Boruta RJ, et al. (2013) Sickle Erythrocytes Target Cytotoxics to Hypoxic Tumor Microvessels and Potentiate a Tumoricidal Response. PLoS ONE 8(1): e52543. doi:10.1371/journal.pone.0052543

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