A Pap Smear for Ovarian Cancer? (2 of 3) (video) American Association for the Advancement of Science Share Print E-Mail Loading video... Caption An overview of the PapGene test. Cancerous cells from ovarian or endometrial tumors are shed into the gynecological tract and collect in the cervix. These cells are captured using a Pap smear brush and their DNA is sequenced. The identification of cancer-specific DNA mutations signifies the presence of a gynecologic malignancy. This video relates to a paper that appeared in the Jan. 9, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by I. Kinde at Johns Hopkins Kimmel Cancer Center in Baltimore, Md., and colleagues was titled, "Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers." Credit Video courtesy of Elizabeth Cook Usage Restrictions Please cite the owner of the video when publishing. This video may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.