Clues to Early Breast Cancer Spread (1 of 1) (image) American Association for the Advancement of Science Share Print E-Mail Caption KLF6-SV1 is a key molecular switch that drives breast cancer metastasis. This figure illustrates how KLF6-SV1 causes localized breast cancer cell lines to become aggressive, invasive and spread throughout the body in both patients and mouse models of the disease. This image relates to a paper that appeared in the Jan. 23, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by R. Hatami at Mount Sinai School of Medicine in New York, N.Y., and colleagues was titled, "KLF6-SV1 Drives Breast Cancer Metastasis and Is Associated with Poor Survival." Credit Image courtesy of Dr. Raheleh Hatami Usage Restrictions Please cite the owner of the image when publishing. This image may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.