Contact: Julia Evangelou Strait
Washington University School of Medicine
Caption: Investigational cancer drugs, IAP antagonists, may increase the risk of tumors spreading to bone. Tumors often cause bone loss, but IAP antagonist treatment accelerates the problem. The images show a bone with a tumor from a mouse treated with IAP antagonist BV6. The bone destruction is substantial, with gaping holes (left) and near total loss of the interior spongy bone (right).
Credit: Chang Yang, M.D., Ph.D.
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