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Contact: Karen Kreeger
University of Pennsylvania School of Medicine

Reprogramming Cells to Fight Diabetes

Caption: Treatment of human islets with the histone methyltransferase inhibitor Adox results in co-localization of the beta-cell specific transcription factor PDX1 (white) in a substantial sub-population of glucagon-positive cells (red), indicating partial endocrine cell-fate conversion.

Credit: Nuria Bramswig, Perelman School of Medicine, University of Pennsylvania

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