Contact: Cathy Kolf
Johns Hopkins Medicine
Caption: When the fusogenic protein Eff-1 was expressed, a few normally nonfusing cells merged (left). But when Eff-1 was expressed with a protein that could organize cytoskeleton remodeling, fusion was rampant, leading to the formation of giant cells with many nuclei (right).
Credit: From K. Shilagardi, et al., Science, 7 March 2013 (10.1126/science.1234781). Reprinted with permission from AAAS.
Usage Restrictions: May only be used with permission from AAAS.
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