Fusing Cells (image) Johns Hopkins Medicine Caption When the fusogenic protein Eff-1 was expressed, a few normally nonfusing cells merged (left). But when Eff-1 was expressed with a protein that could organize cytoskeleton remodeling, fusion was rampant, leading to the formation of giant cells with many nuclei (right). Credit From K. Shilagardi, et al., Science, 7 March 2013 (10.1126/science.1234781). Reprinted with permission from AAAS. Usage Restrictions May only be used with permission from AAAS. Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.