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Contact: Rachel Pugh
rachel.pugh@childrens.harvard.edu
617-919-3110
Children's Hospital Boston
Caption: The pattern of blue dots indicates that no individual gene was expressed significantly differently in infants who went on to develop bronchopulmonary dysplasia (BPD) as compared with those who didn’t: the dots are as likely to fall above the horizontal line as below it. However, the genes in the chromatin remodeling pathway -- represented by yellow squares -- are significantly more likely to fall below the line, indicating that, as a group, they are "turned on" less often in infants who develop BPD.
Credit: Courtesy Isaac Kohane, MD, PhD, Children's Hospital Boston
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