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Contact: Rex Graham
ragraham@ucsd.edu
858-822-3075
University of California - San Diego
Caption: The enrichment of disease genes is shown for subnetworks or individual genes selected from van de Vijver et al. (a) or Wang et al. (b). Blue bars chart the percentage of disease genes among all genes covered in the markers on the left axis; the red line charts the hypergeometric p-values of enrichment on the right axis. Numbers above the bars are the recovery rates of the known susceptibility genes in each marker set. (c-e) Example discriminative subnetworks containing genes with breast cancer mutations listed in Sjoblom et al. Mutation genes are marked by a plus sign. This is figure 3 from a Molecular Systems Biology published online Oct. 16, 2007. Senior author: Trey Ideker from UC San Diego.
Credit: Trey Ideker / UC San Diego / Molecular Systems Biology
Usage Restrictions: Mandatory credit: Trey Ideker / UC San Diego / Molecular Systems Biology
Related news release: UC San Diego researchers improve accuracy of breast cancer prognoses
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