Transcription Factors Regulating Blood Oxygen Linked to Melanoma Metastases (image) University of North Carolina Health Care Share Print E-Mail Caption Melanoma cells express a higher amount of invasive invadopodia under hypoxic conditions than at normal oxygen levels. Hypoxia is linked to tumor metastasis in melanoma. Credit Kim Lab, UNC School of Medicine Usage Restrictions None Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.