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Contact: Jim Dryden
Washington University School of Medicine

Responders, Nonresponders and Brain Glucose Metabolism

Caption: PET scans of patients successfully treated with vagus nerve stimulation show marked increases in cerebral glucose metabolism after 12 months of treatment (bottom image, red/orange area in yellow circle) in parts of the brainstem thought to be critical in depression. In nonresponders, glucose metabolism decreased in the same brain region (top image, blue/green area in yellow circle).

Credit: Copyright Brain Stimulation 2013, with permission

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