Contact: Anita Kar
Caption: Researchers have unlocked a new door to developing drugs to slow the progression of Parkinson's disease. They have discovered the 3-D structure of the protein Parkin. Mutations in Parkin cause a rare hereditary form of Parkinson's disease and are likely to also be involved in more commonly occurring forms of Parkinson's disease. This new knowledge of Parkin's structure has allowed the scientists to design mutations in Parkin that make it better at recognizing damaged mitochondria and therefore possibly provide better protection for nerve cells.
Credit: Montreal Neurological Institute and Hospital
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