Presenilin and Its Effect on Traffic in Neurons (image) University at Buffalo Share Print E-Mail Caption Expression of human APP in fly larval nerves causes neuronal blockages (arrows, top panel) which are rescued by reductions in presenilin. Expression of human APP in fly larval brains causes cell death (arrows, bottom panel) which are rescued by reductions in presenilin. Credit Shermali Gunawardena Usage Restrictions This image may only be used in conjunction with news reports discussing the research in the associated press release. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.