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Contact: Jules Asher
NIH/National Institute of Mental Health

Insula Activity Predicts Treatment Response

Caption: If a patient's pre-treatment resting brain activity was low in the front part of the insula, on the right side of the brain (red area where green lines converge), it signaled a significantly higher likelihood of remission with CBT and a poor response to escitalopram. Conversely, hyperactivity in the insula predicted remission with escitalopram and a poor response to CBT. Picture shows PET data superimposed on anatomic MRI scan data.

Credit: Helen Mayberg, M.D., Emory University

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