Contact: Nick Zagorski
nzagors1@jhmi.edu
443-287-2251
Johns Hopkins Medical Institutions

Time-Lapse Images Reveal Motile Axons in the Adult Brain

Caption: Left: An image of the cerebellum showing labeled main trunk axons (green) and their target neurons (red), with which they form synapses. This image was not made from a living animal, but rather from a thin slice of fixed brain tissue. Right: Exemplar time-lapse images of axon in the intact brain of a living, anesthetized adult mouse. Both the degree of magnification and the orientation of the axon are different from the ones shown in the left picture. The main axon trunk was stable but a few side-branches showed elongation over a period of several hours (yellow arrowheads).

Credit: Johns Hopkins Medicine

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