Contact: Deborah Williams-Hedges
California Institute of Technology
Caption: The Xist lncRNA (red) recruits proteins responsible for modifying chromatin architecture (green) across the X-chromosome. Xist and its associated proteins coat the entire X-chromosome, forming a distinctive compartment in the nucleus (blue). A new study sheds light on how Xist identifies its target locations and can spread across the chromosome, bringing genes together into these compartments.
Credit: Amy Pandya-Jones and Kathrin Plath
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