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Contact: Catherine Kolf
ckolf@jhmi.edu
443-287-2251
Johns Hopkins Medicine

Active and Inactive PTEN

Caption: PTEN is shown in its active (above) and inactive (below) forms. Phosphate tags (red) on PTEN's tail cause a shape change, which prevents PTEN from binding to the cell's outer envelope (blue) and removing a phosphate from PIP3 (yellow).

Credit: David Bolduc

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