How Protectin D1 Works (image) Duke University Share Print E-Mail Caption A compound derived from the DHA in fish oil -- Protectin D1 (PD1/NPD1) -- offers protection from nerve trauma-induced neuropathic pain by preventing neuronal and glial hyperactivity in the spinal cord. Glial cells, when activated, produce proinflammatory cytokines that may further damage the nerve cells. Credit Ru-Rong Ji and Zhen-Zhong Xu, Duke University Medical Center Usage Restrictions Please credit Ru-Rong Ji and Zhen-Zhong Xu, Duke University Medical Center Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.