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Contact: Jules Asher
NIMHpress@nih.gov
301-443-4536
NIH/National Institute of Mental Health

De novo Damaging Mutations

Caption: Seemingly disparate and scattered throughout the genome, spontaneous, or de novo, damaging mutations found in people with schizophrenia (red) clustered within genes forming a suspected disrupted network in the prefrontal cortex, thought to impair formation of new neurons during prenatal development.

Credit: Mary-Claire King, Ph.D., University of Washington

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Related news release: Stray prenatal gene network suspected in schizophrenia


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