Brain Protein Linked to Memory Loss in Old Age (1 of 3) (video) American Association for the Advancement of Science Share Print E-Mail Loading video... Caption A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, M.D., has found that deficiency of a protein called RbAp48 in the hippocampus is a significant contributor to age-related memory loss and that this form of memory loss is reversible. This sets the stage for further understanding how age-related memory loss differs from Alzheimer's disease. This video relates to a paper that appeared in the Aug. 28, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by E. Pavlopoulos at Columbia University in New York, N.Y., and colleagues was titled, "Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48." Credit Video courtesy of Columbia University Medical Center Usage Restrictions Please cite the owner of the video when publishing. This video may be freely used by reporters as part of news coverage, with proper attribution. Non-reporters must contact Science for permission. Share Print E-Mail Disclaimer: AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert system.