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Brain Protein Linked to Memory Loss in Old Age (1 of 3)

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Caption: A team of Columbia University Medical Center (CUMC) researchers, led by Nobel laureate Eric R. Kandel, M.D., has found that deficiency of a protein called RbAp48 in the hippocampus is a significant contributor to age-related memory loss and that this form of memory loss is reversible. This sets the stage for further understanding how age-related memory loss differs from Alzheimer's disease. This video relates to a paper that appeared in the Aug. 28, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by E. Pavlopoulos at Columbia University in New York, N.Y., and colleagues was titled, "Molecular Mechanism for Age-Related Memory Loss: The Histone-Binding Protein RbAp48."

Credit: Video courtesy of Columbia University Medical Center

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