Contact: Dr. Sarah Chang
Agency for Science, Technology and Research (A*STAR), Singapore
Caption: This is a microscope image of lung cancer cells infected with H1N1 influenza virus. Upon H1N1 viral infection, the cells showed an increase in MHC class I (green) and p53 (red) expression. The co-expression of increased MHC class I and p53 is in yellow. This demonstrates that p53-->ERAP1-->MHC I pathway also occurs in viral infection. It may be interesting to explore the role of p53 in viral infection.
Credit: A*STAR SIgN
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