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Contact: Diana Lutz
Washington University in St. Louis

Patterning the Cell's Skeleton

Caption: WUSTL scientists are using a model system in which the internal skeleton of a cell (its cytoskeleton) is tagged with fluorescent green and cherry red dyes to learn why some skeletons are patterned (left) and others are disorganized (right). They have learned that cells missing the enzyme katanin, named for the katana, or samurai sword, creates and maintains coaligned patterns by cutting microtubles at crossover junctions.


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