Contact: Mika Ono
Scripps Research Institute
Caption: The HIV envelope protein has long been considered one of the most difficult targets in structural biology and of great value for medical science -- particularly for HIV/AIDS vaccine development. Using advanced techniques in both cryo-EM and x-ray crystallography, researchers from The Scripps Research Institute and Weill Medical College of Cornell University have now determined the structure of this protein, here shown bound by broadly neutralizing antibodies against two distinct sites of vulnerability.
Credit: Courtesy of the Wilson lab, The Scripps Research Institute.
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