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Caption: The animation shows a simplified view of lesion development after spinal cord injuries in mice, with and without the resident neural stem cell injury response. The neural stem cells (green) respond to injury by producing progeny that migrate to the lesion site where they contribute to the forming glial scar. Without the neural stem cell response, the injury gradually expands and more nerve fibers are cut off, suggesting that the neural stem cell-derived scar tissue prevents the lesion from expanding. The findings are published in Science, November 1, 2013 by Professor Jonas Frisén and colleagues at Karolinska Institutet in Sweden.
Credit: Mattias Karlén
Usage Restrictions: This movie may only published in connection to reports about the current findings of Jonas Frisén presented in Science, November 2013. Credit must be given to Mattias Karlén.
Related news release: Stem cell scarring aids recovery from spinal cord injury