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Bent Out of Shape: Microchip Device Warps Cells to Spot Cancer (2 of 2)

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Caption: This is a high-speed video of a balloon filled with honey hitting a wall; note the extent to which the balloon is deformed. Similarly, the video shows a cell deforming upon impact in the deformability cytometer system. As the balloon and cell, respectively, impact a surface and deform, information about the material within either body becomes discernible. This video relates to a paper that appeared in the Nov. 20, 2013, issue of Science Translational Medicine, published by AAAS. The paper, by Dr. H.T.K. Tse at University of California, Los Angeles in Los Angeles, Calif., and colleagues was titled, “Quantitative Diagnosis of Malignant Pleural Effusions by Single-Cell Mechanophenotyping.”

Credit: Courtesy of the Di Carlo Laboratory at UCLA

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